Tiny Warrior, Big Victory: Ava’s Journey with SCID

Some heroes wear capes. Others wear hospital bracelets and a brave smile.

When Ava was born, her parents had no idea they’d be navigating the world of rare diseases. But at just a few weeks old, Ava began showing signs that something wasn’t right. After a series of tests and doctor visits, they received a diagnosis that would change their lives: Severe Combined Immunodeficiency (SCID).

Often referred to as “bubble baby disease,” SCID is one of the most severe forms of primary immunodeficiency. Children born with SCID are missing key components of the immune system, leaving them defenseless against infections that most of us fight off without a second thought. Without treatment, the condition is life-threatening in early infancy.

A Road Paved with Challenges

For Ava’s family, life quickly became a whirlwind of hospital stays, lab tests, and urgent decisions. The treatment plan included a hematopoietic stem cell transplant at UCSF Benioff Children’s Hospital—a critical step toward building a functioning immune system.

Ava bravely faced months in the hospital, enduring complications like graft-versus-host disease. There were countless moments of fear and frustration. But through it all, her fighting spirit never wavered.

From Isolation to Inspiration

Today, Ava is thriving. At six years old, she’s healthy, curious, and full of life. She recently earned the Principal’s Award in her kindergarten class—proof that what once felt impossible is now reality.

Thanks to early diagnosis, specialized care, and the love of her family, Ava beat the odds. And while her immune system will always require monitoring, her story shines a light of hope for other families walking similar paths.

Why Ava’s Story Matters

SCID is rare, but awareness and newborn screening make all the difference. With early diagnosis and timely treatment, many children with SCID can live full, healthy lives. Ava’s story reminds us of what’s possible when medical breakthroughs meet fierce parental advocacy and community support.

At the Yellow Bear Foundation, we’re committed to amplifying stories like Ava’s. Because behind every diagnosis is a child with dreams, a family fighting for answers, and a future worth protecting.

Join us in spreading awareness about SCID and other rare primary immunodeficiencies. Together, we can help more families go from fear to hope, and from diagnosis to thriving.

✳️ Story adapted from the Immune Deficiency Foundation’s SCID success stories.